Town & Gown Institute of Innovation for the Future at Hiroshima University was launched in April 2022 as a joint education and research facility on campus to support Town & Gown Office (TGO) project. To build a new regional development model that will lead social changes for a sustainable society, we conduct research on technological challenges contributing to the SDGs, EBPM/DX research to accelerate innovation and social integration, and promote regional development research for social integration in regional fields, with the aim of fostering entrepreneurs who can create innovations and integrate them into the society.